Northern Region or variations may refer to:
Africa
Northern Region (Ghana)
Northern Region, Eastern Cape, South Africa
Northern Region, Malawi
Northern Region, Nigeria (former)
Northern Region, Uganda
Nord Region, Burkina Faso
North Region, Cameroon
Americas
Northern Region, Manitoba, Canada, a region situated on the Canadian Shield including Manitoba's Hudson Bay coastline
AAA Northern Region, a sports league of large high schools in Virginia, United States
North Region, Brazil, an official grouping of states for economic and statistical purposes
Elsewhere
Northern Region, Malta
Northern Region (Sydney), alternative name for the northern suburb of Sydney in Australia
Northern Region Film and Television Archive, an English organisation
Uttar Pradesh (lit. 'northern region'), a state in northern India
North Region, Singapore
VUSO, the Ally occupied northern region of European Russia.