Joseph or Joe Powell may refer to:
Joseph Powell (painter) (1780–1834), English watercolourist, sometimes called "John Powell"
Joseph Powell (congressman) (1828–1904), U.S. Representative from Pennsylvania
Joe Powell (Australian footballer) (1868–1945), Australian rules footballer
Joe Powell (footballer, born 1870) (1870–1896), English footballer
Joe Powell (stunt performer) (1922–2016), English stuntman and actor
Jody Powell (Joseph Lester Powell, 1943–2009), White House Press Secretary during the presidency of Jimmy Carter
Joe Powell (rugby union) (born 1994), Australian rugby union player
Joe Powell (American football) (born 1994), American football defensive back
Joe Powell (footballer, born 1998), English footballer for Burton Albion
Joe Powell (politician), British politician