Central Plain or Central Plains may refer to:

Regions

Zhongyuan, a plain in Northern China in the lower reaches of the Yellow River which was the cradle of Chinese civilisation

Central Plains Economic Zone

Central Plain (Antigua), home to the majority of the country's population

Central Plain (Wisconsin), one of the geographical regions of Wisconsin

Central Plains Region, an informal geographic region of the Canadian province of Manitoba

Central Plains Water, an enhancement scheme for the "Central Plains" of Canterbury, New Zealand

The South Central Plains taking up most of Piney Woods, a forest terrestrial ecoregion in the Southern United States.

Central Thailand, a plain in Thailand

Great Plains, in North America, a portion of which is known as Central Plain

Central Plains USD 112, a unified school district including various communities in central Kansas, USA