William Howe may refer to:
William Howe, 5th Viscount Howe (1729–1814), British general during American Revolutionary War
William Howe (architect) (1803–1852), patented Howe truss for covered bridges
William Howe (mayor) (1864–1952), newspaperman in Victoria, Australia
William B. W. Howe (1824–1894), Bishop of South Carolina
William Dean Howe (1916–1982), Canadian Member of Parliament
William F. Howe (lawyer) (1828–1902), American trial lawyer, founded Howe and Hummel
William F. Howe (general) (1888–1952), American stockbroker and military leader during World Wars
William H. Howe (1837–1907), American Union Army soldier during the Civil War and Medal of Honor recipient
William Henry Howe (1846–1929), American painter
William T. Howe (1835–1918), farmer and political figure in New Brunswick, Canada
William Wirt Howe (1833–1909), Justice of the Louisiana Supreme Court
Bill Howe (1922–2007), baseball player at Yale University
W. B. W. Howe Jr., (1851-1912), architect, son of the bishop