Sierra Madre (Spanish, 'mother mountain range') may refer to:
Places and mountains
Mexico
Sierra Madre Occidental, a mountain range in northwestern Mexico and southern Arizona
Sierra Madre Oriental, a mountain range in northeastern Mexico
Sierra Madre de Oaxaca, a mountain range in south-central Mexico
Sierra Madre del Sur, a mountain range in southern Mexico
Central America
Sierra Madre, known in Mexico as Sierra Madre de Chiapas, a mountain range which extends from southeastern Mexico and crosses southern Guatemala, northern El Salvador, and western Honduras
Philippines
Sierra Madre (Philippines), a mountain range on Luzon island
United States
Sierra Madre Mountains (California), a mountain range in the state of California
Sierra Madre Fault Zone, at the boundary to the San Gabriel Valley and San Fernando Valley
1991 Sierra Madre earthquake
Sierra Madre, California, a town in Los Angeles County located at the foot of the San Gabriel Mountains
Sierra Madre Boulevard
Sierra Madre Villa station, Los Angeles Metro Rail A Line station.
Sierra Madre Line, a former railway line
Sierra Madre Range (Wyoming), a mountain range in the south central portion of the state
Other uses
Sierra Madre sparrow, Xenospiza baileyi, an endangered American bird
Sierra Madre ground squirrel, Callospermophilus madrensis, a species of rodent
Sierra Madre Casino, a fictional location in the Fallout: New Vegas video game
BRP Sierra Madre (LT-57), a Philippine Navy ship formerly USS Harnett County (LST-821), deliberately run aground on the Second Thomas Shoal of the Spratly Islands