Mary Margaret is a feminine given name. Notable people with the name include:
Mary Margaret Busk (1779–1863), English writer and translator
Mary Margaret Conway, American political scientist
Mary Margaret Francis (1924–2000), British author
Mary Margaret Funk, American writer and advocate of inter-religious dialogue
Mary Margaret Haugen (born 1941), American politician
Mary Margaret Heaton (1836–1883), English art historian
Mary-Margaret Humes (born 1954), American actress and beauty pageant titleholder
Mary Margaret Kaye (1908–2004), British writer
Mary Margaret McBride (1899–1976), American radio interview host and writer
Mary Margaret McCabe (born 1948), English emerita professor of ancient philosophy
Mary Margaret McKeown (born 1951), American circuit judge
Mary-Margaret McMahon (born 1966), Canadian politician
Mary Margaret Milner, birth name of Margaret Richardson (lawyer) (1943–2021), American tax lawyer
Mary Margaret Oliver (born 1948), American politician
Mary Margaret O'Hara (born late 1950s), Canadian singer-songwriter, actress, and composer
Mary Margaret O'Reilly (1865–1949), American civil servant
Mary Margaret Truman (1924–2008), American classical soprano, actress, journalist, radio- and television personality, writer, and socialite; only child of Harry S. Truman
Mary Margaret Whipple (born 1940), American former politician