Little Joe may refer to:
People
Little Joe McLerran (born 1983), American singer, guitarist and recording artist
Joe Arenas (1925–2020), American retired National Football League player
Little Joe Blue (1934–1990), American blues singer and guitarist, born Joseph Valery Jr.
Little Joe Cook (1922–2014), American R&B singer and songwriter
Joe Dallesandro (born 1948), American actor and counterculture icon, associated with Andy Warhol and Lou Reed
Joseph DeFede (1934–2012), New York City mob boss turned informant
Joe Hamilton (basketball) (born 1948), American retired basketball player
"Little Joe" Hupp, a member of the 1960s rock band The Smoke Ring
Joe Morgan (1943–2020), American Major League Baseball player
Joe Pavelski (born 1984), American National Hockey League player
Joe Presko (1928–2019), American retired Major League Baseball pitcher
Joe Washington (born 1953), American retired National Football League player
Joe Weatherly (1922–1964), American stock car racing driver
Joseph Wentworth, early 20th century American college football player and coach
Joe Yeager (1875–1937), American Major League Baseball player
Ring name of Joe Acton (1852–1917), British professional wrestler and world champion
Little Joe (singer) (born 1940), stage name of American tejano performer José María De León Hernández
Ranking Joe (born 1959), also known as Little Joe, Jamaican reggae DJ Joseph Jackson
J.O.E. (1986–2011), Jamaican reggae singer formerly known as 'Lil Joe' or 'Little Joe'
Little Papa Joe (1935–2018), American blues guitarist and singer
Little Son Joe (1900–1961), American blues guitarist and composer
Arts and entertainment
Fictional characters
Little Joe (character), Joseph, the youngest Cartwright son in the television series Bonanza
Little Joe (Veggietales), a Veggietales character
Little Joe Jackson, the protagonist of the 1940 Broadway musical Cabin in the Sky and the 1943 film Cabin in the Sky
Little Joe, in Team Umizoomi
A character in the 1970 film Kelly's Heroes
The title character of "Little Joe the Wrangler", an American cowboy song
Other arts and entertainment
Little Joe (comic strip), a Western comic strip created in the early 1930s by Ed Leffingwell
Little Joe (film), a 2019 British-Austrian drama film
"Little Joe", a track from the album Screaming Life by Soundgarden
Places
Mount Little Joe, Victoria, Australia - see Warburton, Victoria
Little Joe River, Minnesota
Rockets and missiles
KAN Little Joe, a US Navy surface-to-air missile
Little Joe (rocket), a 1959 booster rocket used in the US Mercury space program
Little Joe II, used in the US Apollo space program
Locomotives
Little Joe (Baltimore and Ohio locomotive), the last 0-4-0 steam locomotives built for the Baltimore and Ohio Railroad
Little Joe (electric locomotive), a type of railroad electric locomotive
Other uses
Nickname for four in a game of craps
Little Joe's, a former Italian restaurant (1928–1998) in Los Angeles, California