The current Ambassador to the Holy See is Brian Burch, who replaced the ad interim Chargé d'Affaires Laura Hochla, on September 13, 2025. The Holy See is represented by its apostolic nuncio, Archbishop Gabriele Giordano Caccia, who assumed office in March 2026. The U.S. Embassy to the Holy See is located in Rome, in the Villa Domiziana. The Nunciature to the United States is located in Washington, D.C., at 3339 Massachusetts Avenue, N.W.