Great Eastern may refer to:

Transport

SS Great Eastern, a steamship built by Isambard Kingdom Brunel in 1858, the largest ship of its era

Great Eastern Railway, a defunct English railway company formed in 1862

First Great Eastern, a defunct train operating company on the Great Eastern Main Line

Great Eastern Main Line, a British railway line

The Great Eastern, a bridge laying tank of World War II

Arts and entertainment

The Great Eastern (radio show), that ran from 1994 to 1999 on CBC Radio One

The Great Eastern (album), a 2000 album by the Scottish band The Delgados

The Great Eastern (Rodman novel), a 2019 novel by Howard A. Rodman

The Great Eastern (Embirikos novel), a 1990-1992 novel by Andreas Embirikos

Other uses

Great Eastern Hotel (disambiguation)

Great Eastern Life, an insurance company in Singapore and Malaysia