Adrian Smith may refer to:

Adrian Smith (basketball) (1936–2026), American basketball player

Adrian Smith (architect) (born 1944), American architect

Sir Adrian Smith (statistician) (born 1946), English statistician and academic

Adrian Smith (musician) (born 1957), English musician, member of the band Iron Maiden

Adrian Smith (strongman) (born 1964), British professional strongman competitor

Adrian Smith (politician) (born 1970), United States representative from Nebraska's 3rd congressional district

Adrian Smith (illustrator), British illustrator of game materials

Adrian Smith (rugby union) (born 1987), New Zealand rugby player