South Central may refer to:
Entertainment
South Central (film), a 1992 film starring Glenn Plummer
South Central (soundtrack), a soundtrack album from the film
South Central (TV series), a 1994 comedy-drama starring Larenz Tate
Places
South Central China, a region of the People's Republic of China
South Central Province, Maldives
South Central United States
South Central Alaska, a region containing the Anchorage metropolitan area, U.S.
South Los Angeles, an area in Los Angeles, California, U.S., formerly South Central Los Angeles
South Central, Wichita, Kansas, U.S.
South Central Coast, a region of Vietnam
Rail transport
South Central Railway zone, a part of Indian Railways
Connex South Central, a train operating company in England from 1996 until 2001
Southern (train operating company), a train operating company in England named South Central from 2001 until 2004
Other uses
South Central Conference (disambiguation)
South Central Region (WFTDA)